human ACOX1 shRNA silencing AAV

Cat. No: shAAV-200219

Availability: 4-5 weeks

Name: AAV-h-ACOX1-shRNA

This is an AAV expressing shRNA for silencing of Human ACOX1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ACOX1
Gene Name: acyl-CoA oxidase 1
Gene ID: 51
Gene Synonyms: ACOX; PALMCOX; SCOX
ORF Size: 1983 bp
RefSeq#: NM_004035
Gene Description: ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.464137
HGNC ID: HGNC:119