human ABCG4 shRNA silencing AAV

Cat. No: shAAV-200100

Availability: 6-8 weeks

Name: AAV-h-ABCG4-shRNA

This is an AAV expressing shRNA for silencing of Human ABCG4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCG4
Gene Name: ATP binding cassette subfamily G member 4
Gene ID: 64137
Gene Synonyms: WHITE2
ORF Size: 1941 bp
RefSeq#: NM_022169
Gene Description: ABCG4 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.
UniGene ID: Hs.126378
HGNC ID: HGNC:13884