human ABCC4 shRNA silencing AAV

Cat. No: shAAV-200080

Availability: 4-5 weeks

Name: AAV-h-ABCC4-shRNA

This is an AAV expressing shRNA for silencing of Human ABCC4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCC4
Gene Name: ATP binding cassette subfamily C member 4
Gene ID: 10257
Gene Synonyms: MOAT-B; MOATB; MRP4
ORF Size: 2580 bp
RefSeq#: NM_005845
Gene Description: ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
UniGene ID: Hs.508423
HGNC ID: HGNC:55