human ABCC3 shRNA silencing AAV

Cat. No: shAAV-200078

Availability: 6-8 weeks

Name: AAV-h-ABCC3-shRNA

This is an AAV expressing shRNA for silencing of Human ABCC3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCC3
Gene Name: ATP binding cassette subfamily C member 3
Gene ID: 8714
Gene Synonyms: ABC31; cMOAT2; EST90757; MLP2; MOAT-D; MRP3
ORF Size: 4584 bp
RefSeq#: NM_003786
Gene Description: ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
UniGene ID: Hs.463421
HGNC ID: HGNC:54