human ABCB9 shRNA silencing AAV

Cat. No: shAAV-200069

Availability: 4-5 weeks

Name: AAV-h-ABCB9-shRNA

This is an AAV expressing shRNA for silencing of Human ABCB9.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCB9
Gene Name: ATP binding cassette subfamily B member 9
Gene ID: 23457
Gene Synonyms: EST122234; TAPL
ORF Size: 2310 bp
RefSeq#: NM_019624
Gene Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities.
UniGene ID: Hs.511951
HGNC ID: HGNC:50