human ABCA5 shRNA silencing AAV

Cat. No: shAAV-200051

Availability: 4-5 weeks

Name: AAV-h-ABCA5-shRNA

This is an AAV expressing shRNA for silencing of Human ABCA5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCA5
Gene Name: ATP binding cassette subfamily A member 5
Gene ID: 23461
Gene Synonyms: ABC13; EST90625
ORF Size: 4926 bp
RefSeq#: NM_018672
Gene Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
UniGene ID: Hs.421474
HGNC ID: HGNC:35