human ABCA3 shRNA silencing AAV

Cat. No: shAAV-200046

Availability: 4-5 weeks

Name: AAV-h-ABCA3-shRNA

This is an AAV expressing shRNA for silencing of Human ABCA3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCA3
Gene Name: ATP binding cassette subfamily A member 3
Gene ID: 21
Gene Synonyms: ABC-C; ABC3; EST111653; LBM180; SMDP3
ORF Size: 5115 bp
RefSeq#: NM_001089
Gene Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death.
UniGene ID: Hs.26630
HGNC ID: HGNC:33