human AATF shRNA silencing AAV

Cat. No: shAAV-200038

Availability: 4-5 weeks

Name: AAV-h-AATF-shRNA

This is an AAV expressing shRNA for silencing of Human AATF.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AATF
Gene Name: apoptosis antagonizing transcription factor
Gene ID: 26574
Gene Synonyms: BFR2; CHE-1; CHE1; DED
ORF Size: 1683 bp
RefSeq#: NM_012138
Gene Description: AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
UniGene ID: Hs.195740
HGNC ID: HGNC:19235