human AASDHPPT shRNA silencing AAV

Cat. No: shAAV-200034

Availability: 4-5 weeks

Name: AAV-h-AASDHPPT-shRNA

This is an AAV expressing shRNA for silencing of Human AASDHPPT.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AASDHPPT
Gene Name: aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Gene ID: 60496
Gene Synonyms: AASD-PPT; ACPS; CGI-80; LYS2; LYS5
ORF Size: 930 bp
RefSeq#: NM_015423
Gene Description: AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
UniGene ID: Hs.524009
HGNC ID: HGNC:14235