human AARS2 shRNA silencing AAV

Cat. No: shAAV-200029

Availability: 4-5 weeks

Name: AAV-h-AARS2-shRNA

This is an AAV expressing shRNA for silencing of Human AARS2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AARS2
Gene Name: alanyl-tRNA synthetase 2, mitochondrial
Gene ID: 57505
Gene Synonyms: AARSL; COXPD8; LKENP; MT-ALARS; MTALARS
ORF Size: 2958 bp
RefSeq#: NM_020745
Gene Description: AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
UniGene ID: Hs.158381
HGNC ID: HGNC:21022