human A2ML1 shRNA silencing AAV

Cat. No: shAAV-200007

Availability: 6-8 weeks

Name: AAV-h-A2ML1-shRNA

This is an AAV expressing shRNA for silencing of Human A2ML1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: A2ML1
Gene Name: alpha-2-macroglobulin like 1
Gene ID: 144568
Gene Synonyms: CPAMD9
ORF Size: 4365 bp
RefSeq#: NM_144670
Gene Description: A2ML1 encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID: 20805888). Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.620532
HGNC ID: HGNC:23336

Product	Cat No.
Ad-h-A2ML1	ADV-200007
Ad-h-A2ML1-shRNA	shADV-200007