human A1CF shRNA silencing AAV

Cat. No: shAAV-200003

Availability: 4-5 weeks

Name: AAV-h-A1CF-shRNA

This is an AAV expressing shRNA for silencing of Human A1CF.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: A1CF
Gene Name: APOBEC1 complementation factor
Gene ID: 29974
Gene Synonyms: ACF; ACF64; ACF65; APOBEC1CF; ASP
ORF Size: 1785 bp
RefSeq#: NM_138933
Gene Description: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
UniGene ID: Hs.499643