Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Rat

Gene Symbol

Mx1

Gene Name

myxovirus (influenza virus) resistance 1

Gene ID

24575

Gene Synonyms

IFI78

ORF Size

1959 bp

RefSeq#

BC099784

Gene Description

Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean-Congo hemorrhagic fever virus CCHFV|Function: May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation.