mouse PPARGC1A Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-280991
Availability:
Immediate
Name:
Ad-m-PPARGC1A
This is an Adenovirus expressing Mouse Ppargc1a.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ppargc1a
- Gene Name
- peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
- Gene ID
- 19017
- Gene Synonyms
- A830037N07Rik; ENSMUSG00000079510; Gm11133; PGC-1; Pgc-1alpha; Pgc1; Pgco1; PPARGC-1-alpha; Ppargc1
- ORF Size
- 2394 bp
- RefSeq#
- BC066868
- Gene Description
- Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.
- UniGene ID
- Mm.441196
Product Citations
This product is referenced in the following publications:
- L Xu, X Ma, A Bagattin, E Muelle (2016). The transcriptional coactivator PGC1a protects against hyperthermic stress via cooperation with the heat shock factor HSF. Cell Death & Disease.
- Jared Iacovelli, etc (2016). PGC-1a Induces Human RPE Oxidative Metabolism and Antioxidant CapacityPGC-1a Controls RPE Metabolism. Investigative Ophthalmology & Visual Science.
- M Webb, etc (2018). A Novel Mitophagy Assay for Skeletal Myotubes. J Neurol Neurosurg.
- TI Lima, etc (2019). Essential role of PGC-1a/PPARß axis in Ucp3 gene induction. The Journal of Physiology.
- TI Lima, etc (2019). Opposing action of NCoR1 and PGC-1a in mitochondrial redox homeostasis. Free Radical Biology and Medicine.
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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