Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Abcg2

Gene Name

ATP-binding cassette, sub-family G (WHITE), member 2

Gene ID

26357

Gene Synonyms

ABC15; ABCP; AI428558; BCRP; Bcrp1; MXR; MXR1

ORF Size

1974 bp

RefSeq#

BC053730

Gene Description

Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

UniGene ID

Mm.333096