Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Dcaf7

Gene Name

DDB1 and CUL4 associated factor 7

Gene ID

71833

Gene Synonyms

1700012F10Rik; 2610037L01Rik; C86529; HAN11; Wdr68

ORF Size

1026 bp

RefSeq#

BC048165

Gene Description

Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

UniGene ID

Mm.307455