Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Tinf2

Gene Name

Terf1 (TRF1)-interacting nuclear factor 2

Gene ID

28113

Gene Synonyms

AW552114; D14Wsu146e; Tin2

ORF Size

1245 bp

RefSeq#

BC030347

Gene Description

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.

UniGene ID

Mm.29346