Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Spdya

Gene Name

speedy/RINGO cell cycle regulator family, member A

Gene ID

70891

Gene Synonyms

4921517J08Rik; 4930548B21Rik; GS4; MLZ-465; Spdy1

ORF Size

852 bp

RefSeq#

BC147719

Gene Description

Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2.

UniGene ID

Mm.477599