Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ptn

Gene Name

pleiotrophin

Gene ID

19242

Gene Synonyms

HARP; HB-GAM; HBBN; HBGF-8; HBNF; OSF; Osf-1; Osf1

ORF Size

507 bp

RefSeq#

BC061695

Gene Description

Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

UniGene ID

Mm.279690