Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Mkl1

Gene Name

MKL (megakaryoblastic leukemia)/myocardin-like 1

Gene ID

223701

Gene Synonyms

AMKL; Bsac; Mal; Mrtf-A

ORF Size

2790 bp

RefSeq#

BC050941

Gene Description

Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity).

UniGene ID

Mm.439814