Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ccr4

Gene Name

chemokine (C-C motif) receptor 4

Gene ID

12773

Gene Synonyms

C-C CKR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r

ORF Size

1083 bp

RefSeq#

BC119171

Gene Description

High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

UniGene ID

Mm.1337