Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Bphl

Gene Name

biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)

Gene ID

68021

Gene Synonyms

2010012D11Rik; 5730533B08Rik; AI115341

ORF Size

876 bp

RefSeq#

BC025162

Gene Description

Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.

UniGene ID

Mm.140243