Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DYX1C1

Gene Name

dyslexia susceptibility 1 candidate 1

Gene ID

161582

Gene Synonyms

CILD25; DNAAF4; DYX1; DYXC1; EKN1; RD

ORF Size

1146 bp

RefSeq#

BC062564

Gene Description

DYX1C1 encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.

UniGene ID

Hs.126403

HGNC ID

HGNC:21493