Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HPGD

Gene Name

hydroxyprostaglandin dehydrogenase 15-(NAD)

Gene ID

3248

Gene Synonyms

15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1

ORF Size

801 bp

RefSeq#

BC018986

Gene Description

HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.596913

HGNC ID

HGNC:5154