Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

YWHAZ

Gene Name

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Gene ID

7534

Gene Synonyms

14-3-3-zeta; HEL-S-3; HEL-S-93; HEL4; KCIP-1; YWHAD

ORF Size

738 bp

RefSeq#

BC099904

Gene Description

YWHAZ product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

UniGene ID

Hs.492407

HGNC ID

HGNC:12855