Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

UNC5B

Gene Name

unc-5 netrin receptor B

Gene ID

219699

Gene Synonyms

p53RDL1; UNC5H2

ORF Size

2838 bp

RefSeq#

BC166694

Gene Description

UNC5B encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

UniGene ID

Hs.522997

HGNC ID

HGNC:12568