Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

UHMK1

Gene Name

U2AF homology motif kinase 1

Gene ID

127933

Gene Synonyms

KIS; KIST; P-CIP2

ORF Size

1035 bp

RefSeq#

BC026046

Gene Description

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.127310

HGNC ID

HGNC:19683