Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

U2AF1

Gene Name

U2 small nuclear RNA auxiliary factor 1

Gene ID

7307

Gene Synonyms

FP793; RN; RNU2AF1; U2AF35; U2AFBP

ORF Size

504 bp

RefSeq#

BC005915

Gene Description

U2AF1 belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF1 encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniGene ID

Hs.365116

HGNC ID

HGNC:12453