Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TWIST1

Gene Name

twist family bHLH transcription factor 1

Gene ID

7291

Gene Synonyms

ACS3; bHLHa38; BPES2; BPES3; CRS; CRS1; CSO; SCS; TWIST

ORF Size

609 bp

RefSeq#

BC036704

Gene Description

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

UniGene ID

Hs.66744

HGNC ID

HGNC:12428