Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TRIM63

Gene Name

tripartite motif containing 63

Gene ID

84676

Gene Synonyms

IRF; MURF1; MURF2; RNF28; SMRZ

ORF Size

1062 bp

RefSeq#

BC080529

Gene Description

TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

UniGene ID

Hs.279709

HGNC ID

HGNC:16007