Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TCN2

Gene Name

transcobalamin 2

Gene ID

6948

Gene Synonyms

D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII

ORF Size

1203 bp

RefSeq#

BC011239

Gene Description

TCN2 encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.417948

HGNC ID

HGNC:11653