human TCL1A Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-225227
Availability:
3-5 weeks
Name:
Ad-h-TCL1A
This is an Adenovirus expressing Human TCL1A.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TCL1A
- Gene Name
- T-cell leukemia/lymphoma 1A
- Gene ID
- 8115
- Gene Synonyms
- TCL1
- ORF Size
- 345 bp
- RefSeq#
- BC014024
- Gene Description
- Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 (PubMed 9520462)). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 (PubMed 10983986)).(supplied by OMIM, Jul 2010)
- UniGene ID
- Hs.2484
- HGNC ID
- HGNC:11648
Related Products
Product | Cat No. |
---|---|
AAV-h-TCL1A | AAV-225227 |
AAV-h-TCL1A-shRNA | shAAV-225227 |
Ad-h-TCL1A-shRNA | shADV-225227 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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