Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SYTL2

Gene Name

synaptotagmin like 2

Gene ID

54843

Gene Synonyms

CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A

ORF Size

2808 bp

RefSeq#

BC136450

Gene Description

SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniGene ID

Hs.369520

HGNC ID

HGNC:15585