Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SOD1

Gene Name

superoxide dismutase 1, soluble

Gene ID

6647

Gene Synonyms

ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD

ORF Size

465 bp

RefSeq#

BC001034

Gene Description

SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

UniGene ID

Hs.443914

HGNC ID

HGNC:11179