human SMG7 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-223755
Availability:
3-5 weeks
Name:
Ad-h-SMG7
This is an Adenovirus expressing Human SMG7.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SMG7
- Gene Name
- SMG7, nonsense mediated mRNA decay factor
- Gene ID
- 9887
- Gene Synonyms
- C1orf16; EST1C; SGA56M
- ORF Size
- 3537 bp
- RefSeq#
- BC036381
- Gene Description
- SMG7 encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- UniGene ID
- Hs.591463
- HGNC ID
- HGNC:16792
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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