Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SLC18A2

Gene Name

solute carrier family 18 member A2

Gene ID

6571

Gene Synonyms

SVAT; SVMT; VAT2; VMAT2

ORF Size

1545 bp

RefSeq#

BC108927

Gene Description

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 (PubMed 7905859)). See also SLC18A1 (MIM 193002).(supplied by OMIM, Jan 2011)

UniGene ID

Hs.654476

HGNC ID

HGNC:10935