Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SIVA1

Gene Name

SIVA1 apoptosis inducing factor

Gene ID

10572

Gene Synonyms

CD27BP; SIVA; Siva-1; Siva-2

ORF Size

333 bp

RefSeq#

BC034562

Gene Description

SIVA1 encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.

UniGene ID

Hs.112058

HGNC ID

HGNC:17712