Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SAR1B

Gene Name

secretion associated Ras related GTPase 1B

Gene ID

51128

Gene Synonyms

ANDD; CMRD; GTBPB; SARA2

ORF Size

597 bp

RefSeq#

BC093034

Gene Description

SAR1B is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

UniGene ID

Hs.432984

HGNC ID

HGNC:10535