Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

RRM2

Gene Name

ribonucleotide reductase regulatory subunit M2

Gene ID

6241

Gene Synonyms

R2; RR2; RR2M

ORF Size

1170 bp

RefSeq#

BC030154

Gene Description

RRM2 encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.

UniGene ID

Hs.226390

HGNC ID

HGNC:10452