Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PREX1

Gene Name

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

Gene ID

57580

Gene Synonyms

P-REX1

ORF Size

4977 bp

RefSeq#

BC156402

Gene Description

PREX1 acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

UniGene ID

Hs.153310

HGNC ID

HGNC:32594