Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PPM1G

Gene Name

protein phosphatase, Mg2+/Mn2+ dependent 1G

Gene ID

5496

Gene Synonyms

PP2CG; PP2CGAMMA; PPP2CG

ORF Size

1641 bp

RefSeq#

BC022061

Gene Description

PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

UniGene ID

Hs.643951

HGNC ID

HGNC:9278