Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

POLG2

Gene Name

DNA polymerase gamma 2, accessory subunit

Gene ID

11232

Gene Synonyms

HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB

ORF Size

1458 bp

RefSeq#

BC009194

Gene Description

POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

UniGene ID

Hs.437009

HGNC ID

HGNC:9180