Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PDE10A

Gene Name

phosphodiesterase 10A

Gene ID

10846

Gene Synonyms

ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19

ORF Size

2340 bp

RefSeq#

BC104858

Gene Description

PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

UniGene ID

Hs.348762

HGNC ID

HGNC:8772