Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

OTUB2

Gene Name

OTU deubiquitinase, ubiquitin aldehyde binding 2

Gene ID

78990

Gene Synonyms

C14orf137; OTB2; OTU2

ORF Size

705 bp

RefSeq#

BC068058

Gene Description

OTUB2 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.

UniGene ID

Hs.278815

HGNC ID

HGNC:20351