Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NLRP12

Gene Name

NLR family pyrin domain containing 12

Gene ID

91662

Gene Synonyms

CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2

ORF Size

3186 bp

RefSeq#

BC028069

Gene Description

NLRP12 encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

UniGene ID

Hs.631573

HGNC ID

HGNC:22938