human MYOCD Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-216227
Availability:
Immediate
Name:
Ad-h-MYOCD
This is an Adenovirus expressing Human MYOCD.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MYOCD
- Gene Name
- myocardin
- Gene ID
- 93649
- Gene Synonyms
- MYCD
- ORF Size
- 2961 bp
- RefSeq#
- BC126307
- Gene Description
- MYOCD encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.567641
- HGNC ID
- HGNC:16067
Product Citations
This product is referenced in the following publications:
- Alajbegovic A, etc (2016). Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.
- Zhu B, etc (2017). Similar regulatory mechanisms of caveolins and cavins by myocardin family coactivators in arterial and bladder smooth muscle. PLoS ONE.
- B Zhu, etc (2018). Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. Scientific Reports.
- B Zhu, etc (2020). Antagonistic relationship between the unfolded protein response and myocardin-driven transcription in smooth muscle. Journal of Cellular Physiology.
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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