Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MYO1E

Gene Name

myosin IE

Gene ID

4643

Gene Synonyms

FSGS6; HuncM-IC; MYO1C

ORF Size

3327 bp

RefSeq#

BC098392

Gene Description

MYO1E encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. MYO1E has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

UniGene ID

Hs.654506

HGNC ID

HGNC:7599