Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MLXIPL

Gene Name

MLX interacting protein like

Gene ID

51085

Gene Synonyms

bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH

ORF Size

2166 bp

RefSeq#

BC012925

Gene Description

MLXIPL encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

UniGene ID

Hs.647055

HGNC ID

HGNC:12744