Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MAPK11

Gene Name

mitogen-activated protein kinase 11

Gene ID

5600

Gene Synonyms

p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B

ORF Size

1095 bp

RefSeq#

BC027933

Gene Description

MAPK11 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

UniGene ID

Hs.57732

HGNC ID

HGNC:6873