Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HOPX

Gene Name

HOP homeobox

Gene ID

84525

Gene Synonyms

CAMEO; HOD; HOP; LAGY; NECC1; OB1; SMAP31; TOTO

ORF Size

222 bp

RefSeq#

BC014225

Gene Description

HOPX is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene.

UniGene ID

Hs.654864

HGNC ID

HGNC:24961